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Document 0466
DOCN M9650466
TI Neuropsychiatric HIV-1 infection study: in Kenya and Zaire
cross-sectional phase I and II.
DT 9605
AU Sebit MB; Department of Psychiatry, University of Zimbabwe, Avondale,;
Harare, Zimbabwe.
SO Cent Afr J Med. 1995 Oct;41(10):315-22. Unique Identifier : AIDSLINE
MED/96137271
AB The objective of the study was to determine the prevalence and natural
history of human immunodeficiency virus type 1 (HIV-1) associated
psychiatric, neuropsychological and neurological abnormalities. A total
of 408 subjects were recruited in Nairobi and Kinshasa. The study
consisted of a cross sectional phase and a longitudinal follow up.
Assessment was made by a data collection instrument including six
modules. The intercentre and intracentre reliability in the use of the
each module have been formally evaluated. The mean global score on the
Montgomery-Asberg Depression Rating Scale was significantly higher in
symptomatic seropositive individuals than in matched seronegative
controls. In conclusion, these data suggest that the risk of subtle
cognitive deficits may be increased in asymptomatic stages of HIV-1
infection.
DE Adult AIDS Dementia Complex/COMPLICATIONS/DIAGNOSIS/*EPIDEMIOLOGY
Cross-Sectional Studies Female Follow-Up Studies Human *HIV-1
Kenya/EPIDEMIOLOGY Male Population Surveillance Prevalence Sex
Distribution Support, Non-U.S. Gov't Urban Health Zaire/EPIDEMIOLOGY
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).